Computable lower bounds for deterministic parameter estimation

This paper is primarily tutorial in nature and presents a simple approach(norm minimization under linear constraints) for deriving computable lower bounds on the MSE of deterministic parameter estimators with a clear interpretation of the bounds. We also address the issue of lower bounds tightness in comparison with the MSE of ML estimators and their ability to predict the SNR threshold region. Last, as many practical estimation problems must be regarded as joint detection-estimation problems, we remind that the estimation performance must be conditional on detection performance, leading to the open problem of the fundamental limits of the joint detectionestimation performance

On the influence of detection tests on deterministic parameters estimation

In non-linear estimation problems three distinct regions of operation can be observed. In the asymptotic region, the Mean Square Error (MSE) of Maximum Likelihood Estimators (MLE) is small and, in many cases,close to the Cramer-Rao bound (CRB). In the a priory performance region where the number of independent snapshots and/or the SNR are very low, the MSE is close to that obtained from the prior knowledge about the problem. Between these two extremes, there is an additional transition region where MSE of estimators deteriorates with respect to CRB. The present paper provides exemples of improvement of MSE prediction by CRB, not only in the transition region but also in the a priori region, resulting from introduction of a detection step, which proves that this renement in MSE lower bounds derivation is worth investigating

MSE lower bounds for deterministic parameter estimation

This paper presents a simple approach for deriving computable lower bounds on the MSE of deterministic parameter estimators with a clear interpretation of the bounds. We also address the issue of lower bounds tightness in comparison with the MSE of ML estimators and their ability to predict the SNR threshold region. Last, as many practical estimation problems must be regarded as joint detection-estimation problems, we remind that the estimation performance must be conditional on detection performance

Élaboration de céramiques sans ajouts de frittage par Spark Plasma Sintering pour application en électronique de puissance

Des substrats en carbure de silicium et nitrure d’aluminium ont été élaborés par Spark Plasma Sintering en vue de réaliser des refroidisseurs pour l’électronique de puissance. La température et la pression lors de l’élaboration doivent être maximisées pour atteindre des densités relatives proches des densités théoriques de chaque matériau. Les comportements mécanique et électrique des céramiques ont été établis à l’aide d’une approche microstructures/propriétés. Les porosités jouent un rôle très important sur le comportement mécanique et électrique des matériaux. Il apparaît également que les propriétés électriques de l’AlN SPS sont supérieures à celles de l’AlN fritté conventionnellement montrant que le procédé l’élaboration SPS n’induit pas d’impuretés dans le matériau. Les propriétés électriques du SiC SPS sont largement inférieures à celle du SIC fritté conventionnellement avec du bore comme ajout de frittage indiquant le rôle important de la qualité chimique des poudres utilisées pour le frittage

On Lower Bounds for Non Standard Deterministic Estimation

We consider deterministic parameter estimation and the situation where the probability density function (p.d.f.) parameterized by unknown deterministic parameters results from the marginalization of a joint p.d.f. depending on random variables as well. Unfortunately, in the general case, this marginalization is mathematically intractable, which prevents from using the known standard deterministic lower bounds (LBs) on the mean squared error (MSE). Actually the general case can be tackled by embedding the initial observation space in a hybrid one where any standard LB can be transformed into a modified one fitted to nonstandard deterministic estimation, at the expense of tightness however. Furthermore, these modified LBs (MLBs) appears to include the submatrix of hybrid LBs which is an LB for the deterministic parameters. Moreover, since in the nonstandard estimation, maximum likelihood estimators (MLEs) can be no longer derived, suboptimal nonstandard MLEs (NSMLEs) are proposed as being a substitute. We show that any standard LB on the MSE of MLEs has a nonstandard version lower bounding the MSE of NSMLEs. We provide an analysis of the relative performance of the NSMLEs, as well as a comparison with the MLBs for a large class of estimation problems. Last, the general approach introduced is exemplified, among other things, with a new look at the well-known Gaussian complex observation models

A Constrained Hybrid Cramér-Rao Bound for Parameter Estimation

In statistical signal processing, hybrid parameter estimation refers to the case where the parameters vector to estimate contains both non-random and random parameters. Numerous works have shown the versatility of deterministic constrained Cramér-Rao bound for estimation performance analysis and design of a system of measurement. However in many systems both random and non-random parameters may occur simultaneously. In this communication, we propose a constrained hybrid lower bound which take into account of equality constraint on deterministic parameters. The usefulness of the proposed bound is illustrated with an application to radar Doppler estimation

Recursive hybrid CRB for Markovian systems with time-variant measurement parameters

In statistical signal processing, hybrid parameter estimation refers to the case where the parameters vector to estimate contains both deterministic and random parameters. Lately computationally tractable hybrid Cramér-Rao lower bounds for discrete-time Markovian dynamic systems depending on unknown time invariant deterministic parameters has been released. However in many applications (radar, sonar, telecoms, ...) the unknown deterministic parameters of the measurement model are time variant which prevents from using the aforementioned bounds. It is therefore the aim of this communication to tackle this issue by introducing new computationally tractable hybrid Cramér-Rao lower bounds

Recursive Hybrid Cramér–Rao Bound for Discrete-Time Markovian Dynamic Systems

Abstract—In statistical signal processing, hybrid parameter estimation refers to the case where the parameters vector to estimate contains both non-random and random parameters. As a contribution to the hybrid estimation framework, we introduce a recursive hybrid Cramér–Rao lower bound for discrete-time Markovian dynamic systems depending on unknown deterministic parameters. Additionally, the regularity conditions required for its existence and its use are clarified

Enabling planetary science across light-years. Ariel Definition Study Report

Ariel, the Atmospheric Remote-sensing Infrared Exoplanet Large-survey, was adopted as the fourth medium-class mission in ESA's Cosmic Vision programme to be launched in 2029. During its 4-year mission, Ariel will study what exoplanets are made of, how they formed and how they evolve, by surveying a diverse sample of about 1000 extrasolar planets, simultaneously in visible and infrared wavelengths. It is the first mission dedicated to measuring the chemical composition and thermal structures of hundreds of transiting exoplanets, enabling planetary science far beyond the boundaries of the Solar System. The payload consists of an off-axis Cassegrain telescope (primary mirror 1100 mm x 730 mm ellipse) and two separate instruments (FGS and AIRS) covering simultaneously 0.5-7.8 micron spectral range. The satellite is best placed into an L2 orbit to maximise the thermal stability and the field of regard. The payload module is passively cooled via a series of V-Groove radiators; the detectors for the AIRS are the only items that require active cooling via an active Ne JT cooler. The Ariel payload is developed by a consortium of more than 50 institutes from 16 ESA countries, which include the UK, France, Italy, Belgium, Poland, Spain, Austria, Denmark, Ireland, Portugal, Czech Republic, Hungary, the Netherlands, Sweden, Norway, Estonia, and a NASA contribution

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. For example, a key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process versus those that measure fl ux through the autophagy pathway (i.e., the complete process including the amount and rate of cargo sequestered and degraded). In particular, a block in macroautophagy that results in autophagosome accumulation must be differentiated from stimuli that increase autophagic activity, defi ned as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (inmost higher eukaryotes and some protists such as Dictyostelium ) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the fi eld understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. It is worth emphasizing here that lysosomal digestion is a stage of autophagy and evaluating its competence is a crucial part of the evaluation of autophagic flux, or complete autophagy. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. Along these lines, because of the potential for pleiotropic effects due to blocking autophagy through genetic manipulation it is imperative to delete or knock down more than one autophagy-related gene. In addition, some individual Atg proteins, or groups of proteins, are involved in other cellular pathways so not all Atg proteins can be used as a specific marker for an autophagic process. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field